Systemic Free Fatty Acid Disposal Into Very Low-Density Lipoprotein Triglycerides
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چکیده
منابع مشابه
Systemic Free Fatty Acid Disposal Into Very Low-Density Lipoprotein Triglycerides
We measured the incorporation of systemic free fatty acids (FFA) into circulating very low-density lipoprotein triglycerides (VLDL-TGs) under postabsorptive, postprandial, and walking conditions in humans. Fifty-five men and 85 premenopausal women with BMI 18-24 (lean) and 27-36 kg/m(2) (overweight/obese) received an intravenous bolus injection of [1,1,2,3,3-(2)H5]glycerol (to measure VLDL-TG k...
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The lipid substrate specificity of Manduca sexta lipid transfer particle (LTP) was examined in in vitro lipid transfer assays employing high density lipophorin and human low density lipoprotein (LDL) as donor/acceptor substrates. Unesterified cholesterol was found to exchange spontaneously between these substrate lipoproteins, and the extent of transfer/exchange was not affected by LTP. By cont...
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This manuscript was presented in part at the 31st Annual Meeting of the Council on Arteriosclerosis, American Society for the Study of Arteriosclerosis, American Heart Association. 1977. Circulation. 56(Suppl. III): 22. (Abstr.) Received for publication 2 December 1977 and in revised form 9 February 1978. and apoC) contained by negative staining, many disklike structures. The study demonstrated...
متن کاملVery Low Density Lipoprotein (VLDL)
Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...
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The hamster was developed as a model to study very low density lipoprotein (VLDL) metabolism, since, as is the case in humans, the hamster liver was found to synthesize apoB-100 and not apoB-48. The effect of inhibiting fatty acid synthesis on the hepatic secretion of VLDL triglyceride (TG) and apolipoprotein (apo) B-100 in this model was then investigated. In an in vivo study, hamsters were fe...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2013
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db12-1557